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eanCast: Weekly Neurology

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Official neurology podcast of the European Academy of Neurology (EAN). Expert talks on general neurology, stroke, dementia, epilepsy & many more. New episodes every Monday. For neurology residents, clinicians & researchers. A resource for continuing medical education and lifelong learning.

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29 episodes
weekly
Avg 28 min
English

Episodes 29

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Yesterday · 17 min
Ep. 221: Burnout and Brain Health: The Neurobiology of Stress-Related Exhaustion
Moderator: Luca Cuffaro (Agrigento, Italy) Guest: Ingibjörg Jónsdóttir (Reykjavík, Iceland) In this episode, Luca Cuffaro speaks with Ingibjörg Jónsdóttir about burnout and the neurobiology of stress-related exhaustion. They discuss the clinical features of burnout, the limitations of biological markers such as cortisol, early warning signs including impaired recovery and sleep disturbances, and the importance of recognising work-related stressors in neurological and healthcare practice.
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September 27 · 28 min
Ep. 220: Role of Biomarkers in Translational Neurology for Monitoring Therapeutic Efficacy
Moderator: Lorenzo Barba (Halle Saale, Germany) Guest: Henrik Zetterberg (Gothenburg, Sweden) and Gemma Salvadó (Barcelona, Spain) In this episode, Lorenzo Barba speaks with Henrik Zetterberg and Gemma Salvadó about the role of biomarkers in translational neurology and monitoring therapeutic efficacy. They discuss the clinical application of fluid biomarkers, particularly plasma phosphorylated tau, key diagnostic considerations, and the emerging need for biomarkers of tau pathology, co-pathologies, and treatment response in neurological practice.
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September 20 · 35 min
Ep. 219: Translational Neuroimmunology: Targeted Cellular Therapy for NMDAR Encephalitis
Moderator: Harald Prüß (Berlin, Germany) Guest: Juna de Vries (Rotterdam, Netherlands) In this episode, Harald Prüß speaks with Juna de Vries about targeted cellular therapy for anti-NMDA receptor encephalitis. They discuss key diagnostic features, current immunotherapies, and emerging approaches including CAR T-cell therapy and antibody-selective treatments, with a focus on outcome measures, prognostic assessment, early diagnosis, and their relevance to neurological practice.
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September 13 · 28 min
Ep. 218: Beyond Symptom Control: Gene Therapy for Rare Neurological Disorders
Moderator: Kleopas Kleopa (Nicosia, Cyprus) Guest: Jo Ng (London, UK) In this episode, Kleopas Kleopa speaks with Jo Ng about gene therapy for rare neurological disorders. They discuss the clinical potential of AAV-based therapies, key diagnostic and therapeutic considerations including early diagnosis and treatment timing, and challenges related to safety, immune responses, dosing, and long-term outcomes, with a focus on translating advances into neurological practice.
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September 6 · 16 min
Ep. 217: Translational Neurology Beyond the Bench: Guidelines, Implementation, and Population Impact
Moderator: Kristian Steen Frederiksen (Copenhagen, Denmark) Guest: Katarina Rukavina (Berlin, Germany) In this episode, Kristian Steen Frederiksen speaks with Katarina Rukavina about guideline implementation in neurological practice. They discuss factors influencing adherence to EAN guidelines, the importance of integrating implementation from the start of guideline development, stakeholder and national society engagement, and the potential role of AI in improving access to evidence-based recommendations.
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August 30 · 18 min
Ep. 216: NEUROGED Guidelines
Moderator: Alessandra Fanciulli (Innsbruck, Austria) Guest: Jalesh N. Panicker (London, UK) and Mario Habek (Zagreb, Croatia) In this episode, Alessandra Fanciulli speaks with Jalesh N. Panicker and Mario Habek about the assessment and management of neurogenic urinary and sexual symptoms. They discuss the clinical recognition of urogenital dysfunction in neurological diseases, practical approaches to initial assessment and treatment, and the role of interdisciplinary care in improving neurological practice.
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August 23 · 29 min
Ep. 215: Carpal Tunnel Syndrome Detected by Ultrasound
Moderator: Piergiorgio Lochner (Homburg, Germany) Guest: Stephan Schreiber (Berlin, Germany) In this episode, Piergiorgio Lochner speaks with Stephan Schreiber about carpal tunnel syndrome and its detection by ultrasound. They discuss key clinical and electrophysiological findings, ultrasound assessment of median nerve structure, and the recognition of anatomical or systemic red flags, highlighting the role of nerve ultrasound in diagnosis and neurological practice.
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August 16 · 18 min
Ep. 214: Temporal Arteritis
Moderator: Piergiorgio Lochner (Homburg, Germany) Guest: Arijana Lovrečić-Huzjan (Zagreb, Croatia) In this episode, Piergiorgio Lochner speaks with Arijana Lovrečić-Huzjan about giant cell arteritis and its neurological presentation. They discuss key clinical features, inflammatory markers, and the role of vascular ultrasound in diagnosis, with emphasis on early recognition, differential diagnosis, and timely treatment to prevent visual and cerebrovascular complications.
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August 9 · 31 min
Ep. 213: Plaque / Atherosclerosis at risk
Moderator: Jurgita Valaikienė (Vilnius, Lithuania) Guest: Cristina Duque (Porto, Portugal) In this episode, Jurgita Valaikienė speaks with Cristina Duque about the multimodal assessment of carotid plaques at risk and their role in cerebrovascular disease. They discuss key imaging approaches, the Carotid Plaque-RADS classification, and the identification of high-risk plaque features to support stroke risk stratification and clinical decision-making in neurological practice.
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August 2 · 27 min
Ep. 212: Reversible Cerebral Vasoconstriction Syndrome
Moderator: Jurgita Valaikienė (Vilnius, Lithuania) Guest: Theodoros Mavridis (Dublin, Ireland) In this episode, Jurgita Valaikienė speaks with Theodoros Mavridis about reversible cerebral vasoconstriction syndrome. They discuss its clinical presentation, differential diagnosis and imaging assessment, highlighting key diagnostic challenges, important triggers, and the role of multimodal evaluation for neurological practice.
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July 26 · 40 min
Ep. 211: More Than Words: The Neuroscience of Human Voice
Moderator: Elisa Canu (Milan, Italy) Guest: Sophie Scott (London, United Kingdom) In this episode, Elisa Canu speaks with Sophie Scott about the neural basis of speech and communication, focusing on the evolving role of the motor system within distributed auditory–motor networks. They discuss current evidence relevant to speech perception and production, conversational communication, and vocal behaviours, highlighting implications for the understanding and clinical assessment of communication disorders.
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July 19 · 18 min
Ep. 210: Parkinson’s Disease: Exploring the Interaction between Motor and Language Impairments
Moderator: Elka Stefanova (Belgrade, Serbia) Guest: Maura Panozzo Chiomento (Erfurt, Germany) In this week’s episode, Elka Stefanova and Marua Panozzo Chiomento discuss how Parkinson’s disease affects language and communication. They explore common language impairments, their underlying cognitive and neural mechanisms, approaches to clinical assessment, and their impact on everyday communication and quality of life.
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July 12 · 28 min
Ep. 209: From Gesture to Language: The Evolution of the Motor System-Language Interface
Moderator: Elka Stefanova (Belgrade, Serbia) Guest: Stefano Francesco Cappa (Milan, Italy) In this episode, Elka Stefanova speaks with Stefano Francesco Cappa about the relationship between language and the motor system and its implications for the evolution and neural organisation of language. They discuss evidence from cognitive neuroscience, neuroanatomy, and neurodegenerative disorders, highlighting the role of sensorimotor processes in semantic representation and acquired language dysfunction in neurological practice.
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July 5 · 32 min
Ep. 208: Language: The Bridge Between a Noisy World and a Stable Mind
Moderator: Elisa Canu (Milan, Italy) Guest: Cornelius Weiller (Freiburg, Germany) In this episode, Elisa Canu speaks with Cornelius Weiller about the neural architecture underlying language, concept formation, and the brain’s interaction with the environment. They discuss the role of dorsal, ventral, and semantic pathways, convergence hubs, and their relevance for understanding language processing, cognition, and neurological disorders affecting communication and higher cortical functions.
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June 28 · 32 min
Ep. 207: Pills to face burnout and the role of occupational health therapists
Moderator: Gail Kinman (London, UK) Guest: Alice Accorroni (Geneva, Switzerland) In this episode, Alice Accorroni speaks with Gail Kinman about burnout in healthcare and the role of occupational health psychology in its prevention and management. They discuss the definition and recognition of burnout, key warning signs, and the importance of organisational factors, workplace culture, and leadership in supporting clinician wellbeing and maintaining safe neurological practice.
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June 21 · 19 min
Ep. 206: Genetics in ALS and frontotemporal dementia – from pathophysiology to treatment
Moderator: Cláudia Santos Silva (Lisbon, Portugal) Guest: Andrea Calvo (Turin, Italy) In this episode, Cláudia Santos Silva speaks with Andrea Calvo about the genetics of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). They discuss the shared genetic basis of these disorders, key disease-associated genes, and the role of genetic testing, counselling, and result interpretation in clinical practice, highlighting how genetic discoveries are advancing precision medicine and emerging gene-targeted therapies in ALS and FTD.
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June 14 · 34 min
Ep. 205: Neurofilaments as Biomarkers in ALS and frontotemporal dementia: From Bench to Bedside
Moderator: Raffaele Dubbioso (Naples, Italy) Guest: Andrea Malaspina (London, UK) and Francesco Di Lorenzo (Rome, Italy) In this episode, Raffaele Dubbioso speaks with Andrea Malaspina and Francesco Di Lorenzo about the growing role of neurofilaments as biomarkers in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss the biological basis and clinical interpretation of neurofilament measurements, their diagnostic and prognostic value, and their emerging role in identifying pre-symptomatic disease, monitoring progression, and supporting clinical trials in neurological practice.
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June 7 · 12 min
Ep. 204: Social Cognition in ALS – beyond motor neurons
Moderator: Elisa Canu (Milan, Italy) Guest: Anna Gilioli (Milan, Italy) In this episode, Elisa Canu speaks with Anna Gilioli about social cognition impairment in amyotrophic lateral sclerosis (ALS). They discuss its clinical manifestations, underlying neurobiological mechanisms, and assessment approaches, highlighting the importance of early recognition and its implications for patient management, prognosis, and multidisciplinary neurological care.
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May 31 · 27 min
Ep. 203: Diagnostic challenges in ALS and frontotemporal dementia
Moderator: Valentina Iuzzolino (Naples, Italy) Guest: Elka Stefanova (Belgrade, Serbia) and Mamede de Carvalho (Lisbon, Porugal) In this episode, Valentina Iuzzolino speaks with Elka Stefanova and Mamede de Carvalho about diagnostic challenges in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss clinical heterogeneity, key differential diagnoses and red flags, the role of Gold Coast criteria and neurophysiology in ALS, and the importance of longitudinal clinical assessment and neuroimaging in distinguishing frontotemporal dementia from primary psychiatric disorders.
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May 24 · 26 min
Ep. 202: Clinical neurology Meets AI: Are we prepared?
Moderator: Raphael Wurm (Vienna, Austria) Guest: Roland Wiest (Bern, Switzerland) In this episode, Raphael Wurm speaks with Roland Wiest about how the AI revolution is set to reshape the clinical environment in neurology. They discuss the areas where augmentation and automation are likely to have the greatest impact, including neuroimaging, clinical workflows, and decision support, while exploring how neurologists can prepare themselves and their institutions to translate emerging AI technologies into meaningful improvements for both clinicians and patients.
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