
The Clinical Problem Solvers
The Clinical Problem Solvers
The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
- 26 episodes
- Avg 46 min
- English

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September 14 · 48 minEpisode 476 – Schema Series – Thrombocytopenia
Maddy, Noah, and Youssef discuss a case presented by Mark! Download CPSolvers App here RLRCPSOLVERS
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September 11 · 51 minEpisode 475 – Clinical Unknown Series with Dr. Alec Rezigh
In this episode of the Clinical Unknown Series, Alec challenges the team with a fascinating case of lung–back–brain syndrome. With unexpected twists and a surprising final diagnosis, this case will keep you thinking until the very end. Tune in and see if you can solve the case! To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS
- TCSeptember 10 · 44 min
Episode 473 – Spaced Learning Series: Funky fever
Tune in as Alec, Mengyu, Ethan, and Lera dissect a case of fever! Download CPSolvers App here RLRCPSOLVERS
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September 3 · 36 minEpisode 472 – RLR – 2 Cases – The ?Liver and the ?Brain
Case description Reza and Rabih discuss 2 cases – a ?liver issue and ?brain issue Sponsor This episode is sponsored by Amazon Pharmacy. Learn more at pharmacy.amazon.com/prescribers.
- TCAugust 14 · 1 hr 9 min
Episode 471: Neurology VMR – Found wondering naked in grocery store
We continue our campaign to #EndNeurophobia, with the help of Dr. Helen Shi. This time, Gillian presents a case of a 56 year old man found wondering naked in grocery store. The discussants are Aye and Vale. Gillian is a second-year medical student at the Icahn School of Medicine at Mount Sinai in New York. She studied philosophy and biology as an undergraduate and is fascinated by how clinical reasoning blends logic, uncertainty, and human connection. Her interests are wide-ranging, and she’s explored pediatrics through research in pediatric virology and liver disease. Outside of medicine, she enjoys running, baking (especially anything involving chocolate), and saying hito every dog she passes. Aye is a neurology trainee from Burma, currently working in neurology clinical research at Washington University School of Medicine in St. Louis. She is going to apply neurology residency this year. Through her experiences witnessing the challenges faced by patients in underserved areas and conflict-affected regions, Aye is dedicated to advancing health equity, global neurology, neurohumanities, and excellence in clinical practice, research, and medical education. Outside of work, she enjoys playing piano, jogging along the trails, and listening to music. Vale is a neurology resident from UCSF. She is passionate about LGBTQ+ health, particularly advocating for trans rights, as well as medical education. She would describe herself as an optimist, and outside of medicine, you probably will find her running or talking about pop culture over a glass of wine. Download CPSolvers App here RLRCPSOLVERS
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August 3 · 38 minEpisode 470 – RLR – A Moving Ouch
Case description Reza and Rabih discuss a complex case of a moving ouch, Sponsor This episode is sponsored by Amazon Pharmacy. Learn more at pharmacy.amazon.com/prescribers.
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July 31 · 35 minEpisode 469: SLS – Altered Mental Status
Tune in as Jas, Mukund, Vale, and Anmol dissect a challenging case of altered mental status! Download CPSolvers App here RLRCPSOLVERS
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July 31 · 1 hr 5 minEpisode 468 – The Clinical Unknown Series with Dr. Jeffrey Shen
In this episode, Dr. Jeffrey brings us an extraordinary case with an incredible diagnostic twist that will keep you on the edge of your seat until the very end. Follow along as we unravel the clues and see where the clinical reasoning leads. To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS
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July 16 · 46 minEpisode 467: WDx #43: Clinical Unknown with Kaylin and Sharmin
In this episode, Kuchal joins the WDx team and presents a case of a 35 years old man with convulsions. Download CPSolvers App here RLRCPSOLVERS
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July 13 · 42 minEpisode 466: Antiracism in Medicine – Episode 30 – Mobile Medical Clinics and Democratizing Health Care: Live from the Society of General Internal Medicine’s 2026 Annual Meeting
CPSolvers: Anti-Racism in Medicine Series Episode 30 – Mobile Health Clinics and Democratizing Healthcare: Live from the Society of General Internal Medicine (SGIM) Annual Meeting 2026 Show Notes by Alec J. Calac and Ashley Cooper July 13, 2026 Summary: In this episode, Dr. Shahid Jaffer and Dr. Priya Sarin Gupta join CPSolvers host Ashley Cooper for a live recording of the podcast at the 2026 Society for General Internal Medicine (SGIM) Annual Meeting. This year’s episode, our sixth conducted at SGIM, is focused on democratizing health care by way of mobile health clinics. During this episode, we speak with two experts: (1) Dr. Priya Sarin Gupta who is the Senior Medical Director for Clinical Community Programs at Mass General Brigham, Medical Director for Mobile Health Services at the Kraft Center for Community Health, and an Instructor in Medicine at Harvard Medical School and (2) Dr. Shahid Jaffer, Assistant Professor of Internal Medicine at the University of Minnesota Medical School, Associate Program Director for the University of Minnesota Mobile Health Initiative, and Principal Investigator of the Minnesota Cancer Assessment Mobile Program. This episode is hosted by Ashley Cooper and the show notes for this episode were written by Ashley Cooper and Dr. Alec Calac. Episode Learning Objectives: After listening to this episode, learners will be able to… Identify strategies to engage patients in mobile health care settings to promote healthcare accessibility. Explain how mobile health services function as a critical touchpoint for patients and can help facilitate longitudinal care. Contextualize both local and national data which illuminates mobile health programming as an efficacious tool for addressing structural barriers which patients face, reducing healthcare costs, and cultivating patient trust. Credits: Written and produced by: Dr. Alec Calac and Ashley Cooper Host: Ashley Cooper Infographic: Ashley Cooper Show Notes: Dr. Alec Calac and Ashley Cooper Audio Edits: Ashley Cooper Guests: Dr. Shahid Jaffer, MD and Dr. Priya Sarin Gupta, MD, MPH Guest Biographies: Dr. Shahid Jaffer is an Assistant Professor of Internal Medicine at the University of Minnesota Medical School, board-certified in both Internal Medicine and Addiction Medicine. As Associate Program Director for the University of Minnesota Mobile Health Initiative and Principal Investigator of MCamp (Minnesota Cancer Assessment Mobile Program), he leads a community-centered mobile colorectal cancer screening program that brings evidence-based CRC screening and patient navigation directly to uninsured and underinsured populations within trusted community settings. His clinical work ranges from preventive care and cancer screening to harm reduction and street outreach, serving communities including immigrant populations, migrant and seasonal agricultural workers, unhoused communities, and Indigenous communities in Minnesota and South Dakota. Dr. Priya Sarin Gupta serves as the Senior Medical Director for Clinical Community Programs at Mass General Brigham in the Office of the Chief Medical Officer. As the Medical Director for Mobile Health Services and Special Projects at the Kraft Center for Community Health and an Instructor in Medicine at Harvard Medical School, she combines her expertise with a passion for innovation and empowering the next generation of leaders working at the cross point of public health and medicine. She completed a fellowship in Adolescent and Young Adult Medicine at Johns Hopkins University, a residency in family medicine at Brown University, and received her MPH from Columbia University. Episode Takeaways and Insights Guests Journey to Medicine and Commitment to Providing Linguistically and Culturally-Attuned Care Dr. Jaffer describes global health work as instrumental to his journey to internal medicine. Informed by his commitment to creating accessible healthcare landscapes for patients, Dr. Jaffer currently serves as Associate Program Director for the University of Minnesota Mobile Health Initiative and Principal Investigator of the Minnesota Cancer Assessment Mobile Program. His mobile colorectal cancer screening program strives to bring health services directly to communities at little to no cost, decreasing transportational barriers and uplifting patient health. Dr. Gupta’s path to medicine was shaped by her early travels across the globe which provided her with a profound understanding of the importance of culturally and linguistically-attuned care provision. She now oversees three comprehensive mobile health clinic lines, initially launched in response to the COVID-19 pandemic. The mobile clinics which she supervises tailor treatment to promote patient wellbeing across a range of areas including: management of substance use disorders, preventative health and cancer screenings, and cardiometabolic disease. The mobile clinics aim to serve as a touchpoint for patients to equip them with robust care while simultaneously helping patients establish first-time care or reestablish primary care. Routine engagement, rather than one-off events, promote improved health outcomes. Mobile Health Programming as a Mode of Bolstering Healthcare Accessibility and Addressing Structural Barriers Dr. Gupta delineates mobile health programming as a mode of bolstering healthcare accessibility for patients. She notes that across the three Mass General Brigham Community Care vans which she supervises as Medical Director, there have been 50,000 patient encounters in five years. She also emphasizes that through survey analysis, the program has found that the mobile medical vans are very effective in either bridging patients back to primary medical homes if they previously had PCP’s or establishing new care for patients. Dr. Jaffer describes mobile health care delivery as a potent way to address structural barriers which patients face. By tailoring care to community needs, Dr. Jaffer’s mobile health programs have been able to both attend to urgent care gaps (such as vision services for patients in Minnesota) and also bridge patients to additional forms of care subsequently. Dr. Gupta and Jaffer emphasize the importance of cultivating trust with communities when designing and providing mobile health services. In particular, Dr. Jaffer underscores that it is essential for clinicians to only create screening programs once they have discerned a clear and robust pathway for patients to receive follow-up care for such screening results. Describing mobile care as particularly attentive to the myriad transportational barriers which patients may face, the guests note the importance of making mobile health van services available to communities at a range of times (evening, weekends) and offering walk-in appointments. The Importance of Incorporating Low-Barrier Testing and Patient Navigation Services into Mobile Healthcare Delivery Dr. Jaffer notes that in leading the Minnesota Cancer Assessment Mobile Program (MCAMP) he operates under two key pillars: (1) providing low barrier testing and (2) patient navigation services. In line with this, patients receiving services through MCAMP are able to take a non-invasive colorectal cancer screening test (Cologuard) and also work directly with a community health worker who helps patients navigate the screening process. He notes that their program has a kit return rate of 67% which exceeds the average return rate for Federally Qualified Health Centers which usually sit around 30-40% in terms of Cologuard or FIT (Fecal Immunochemical) test return rates. Recommendations for Clinicians Interested in Beginning a Mobile Health Care Service: Mobile Health Toolkit, Motivational Interviewing, Mobile Health Map, and Sustainability Dr. Gupta shares a Mobile Health toolkit that she co-created on creating mobile clinics in partnership with the Massachusetts Department of Public Health. Dr. Jaffer and Gupta also illuminate how clinicians interested in creating mobile health clinics can partner with community-based organizations in order to provide thoughtful and patient-centered care services. Dr. Jaffer describes how he uses motivational interviewing, tailored messaging, and open conversations about healthcare maintenance to help build patient trust and long-term engagement in care. In response to an audience question, Dr. Jaffer describes how both direct and indirect costs can limit the scale of mobile health services, especially if not under the umbrella of a large health system. However, he offers key strategies that clinicians can use to encourage sustainability of programming: (1) creating partnerships with other clinical and psychosocial services, for instance MCamp partners with University of Minnesota’s pharmacy department and through that partnership is able to provide medication counseling and (2) creating service lines which directly address community needs and thus have community buy-in. In reflecting on sustainability and developing a longitudinal mobile health program, Dr. Gupta encourages clinicians to center grant applications on particular conditions addressed by their service line. She encourages healthcare workers to describe how their programming is moving the needle on health outcomes for particular conditions as opposed to requesting funding for the entire mobile van. Dr. Jaffer shares that there is robust national evidence that mobile health clinics offer a significant reduction in cost-savings. He also shares that there are national databases, such as Mobile Health Map, to help patients locate and access mobile health services. Mobile Health Map also publishes reports on the impact of mobile health clinics across the U.S. Dr. Jaffer concludes by affirming that, to him, the practice of medicine is about partnership and shared decision-making. Dr. Gupta ends by encouraging thought-leaders in medicine to harness innovation and bridge the divide that has historically disenfranchised communities in need of health care. Disclosures The hosts and guests report no relevant financial disclosures. References Gupta, Priya Sarin, Amir M. Mohareb, Christine Valdes, et al. “Expanding COVID-19 Vaccine Access to Underserved Populations through Implementation of Mobile Vaccination Units.” Preventive Medicine 163 (October 2022): 107226. https://doi.org/10.1016/j.ypmed.2022.107226. Gupta, Priya Sarin, Amir M. Mohareb, Christine Valdes, et al. “Mobile Health Services for COVID-19: Counseling, Testing, and Vaccination for Medically Underserved Populations.” American Journal of Public Health 112, no. 11 (2022): 1556–59. https://doi.org/10.2105/AJPH.2022.307021. Jaffer S, Austin R, Kirsch JD. Promoting the health of migrant seasonal agricultural workers in rural Minnesota using a whole-person health approach: a pilot project. Front Public Health. 2025;13:1518686. Published 2025 Apr 2. doi:10.3389/fpubh.2025.1518686 Karout L, Dhar P, Waldron E, et al. Barriers and Facilitators to Accurate Smoking History and Equitable Lung Cancer Screening Uptake Among Hispanic and Latino Populations. J Am Coll Radiol. 2025;22(12):1451-1460. doi:10.1016/j.jacr.2025.08.010 Massachusetts Department of Public Health. “Hosting a Mobile Vaccination Clinic Toolkit.” September 2024. https://www.mass.gov/doc/hosting-a-mobile-vaccination-toolkit/download Harvard Medical School. “Mobile Health Map.” 2026. https://www.mobilehealthmap.org/ Tschampl CA, Wicks JJ, Hodgkin D, et al. Multisite Mobile Addiction Services: Four-Year Outcomes. Int J Environ Res Public Health. 2026;23(6):756. Published 2026 Jun 4. doi:10.3390/ijerph23060756 Show Transcript
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July 9 · 59 minEpisode 465: Schema Episode – Hyperferritinemia
Noah presents a case of hyperferritinemia; tune in as Mark, Youssef, and Maddy work through the diagnostic puzzle. To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS
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July 6 · 31 minEpisode 464 – Special Episode – A Case from the RLR Book – Discipline of Diagnosis
BOOK! A book straight from the hearts and minds of RLR Discipline of Diagnosis – on Amazon Sponsor This episode is sponsored by Amazon Pharmacy. Learn more at pharmacy.amazon.com/prescribers.
- TCJune 23 · 31 min
Episode 463: SLS – Elbow pain
Download CPSolvers app here RLRCPSolvers In the most recent SLS episode, Austin presents a case of a patient with elbow pain to Maryana, David, and Zakariyya. How would you approach and untangle a case like this? What would be your differential diagnosis? Face this diagnostic challenge with us! Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.
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June 18 · 55 minEpisode 462 – The Clinical Unknown Series with Lera Novotnaia
In this episode, Lera—our special Academy member—joins Debora and Rahul to unravel a fascinating case of a young man with neurological symptoms that takes an unexpected and incredible turn. Presented by Mark, this diagnostic journey will keep you guessing until the very end. Don’t miss this compelling path to the final diagnosis! To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS
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June 11 · 43 minEpisode 461: WDx #42: Networking, Negotiating, and Defining Your Values
Sharmin, Kaylin, and Alice dig into how to define and refine your values, why you’re already networking even if you don’t know it, and practical negotiation strategies for women. Download CPSolvers App here RLRCPSOLVERS
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June 1 · 43 minEpisode 460 – RLR – Abrupt Lightheadedness
Episode description RR discuss a fascinating case of abrupt lightheadness Get the book! Discipline of Diagnosis Baseline EKG Presentation EKG Chest x-ray
- TCMay 28 · 34 min
Episode 459 – Schema Episode: Coagulopathy
Youssef presents a case of coagulopathy; tune in as Mark, Noah, and Maddy work through the diagnostic puzzle. To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS
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May 13 · 40 minEpisode 458 – A Case & The Book – Rabih and Reza discuss with Dr. Daniel Kelmenson, a patient with severe hypoxemia
Rabih and Reza discuss with Dr. Daniel Kelmenson, a patient with severe hypoxemia Check out the book The Discipline of Diagnosis
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May 8 · 1 hr 3 minEpisode 457 – The Clinical Unknown Series with Dr. Ravi Singh
In this latest episode, Dr. Ravi Singh unravels the mysterious case of a woman suffering from stomach pain, uncovering a series of unexpected diagnoses along the way. Tune in to experience every twist and revelation! To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS